The new “framework for recognising and valuing high-quality academic work” for ZAP staff resolutely opts for an ambitious HR policy for ZAP staff which, within the institution’s values and needs, leaves room for personal choices, i.e. for a truly differentiated ZAP career framework. It is especially important to introduce this framework now by embedding it systematically in the different phases of the ZAP career: from job application (as in job vacancy texts), over tenure track contracts (including giving attention to the specific situation of international colleagues), to ZAP reviews and BeCo advice on applications for promotion. Only in this way can the new framework come to life throughout the organisation and realise the intended culture change. The specific context of clinical ZAP staff merits special attention. Structural coordination between all partners is, therefore, essential to allow clinical ZAP staff to perform their broad range of tasks with satisfaction and give them the appreciation they deserve.